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Disease in psychiatry where SSRI are contraindicated
Selective Serotonin Reuptake Inhibitors (SSRIs) are commonly prescribed in psychiatry, especially for depression and anxiety disorders. However, there are several psychiatric and medical conditions where SSRIs are contraindicated or should be used with extreme caution due to potential harm. Here are psychiatric conditions where SSRIs are contraindicated or risky : 1. Bipolar Disorder (Especially Bipolar I) – During Depressive Episodes Why contraindicated: SSRIs can induce manic or hypomanic switches and rapid cycling. Precaution: Should only be used with a mood stabilizer (e.g., lithium, valproate). 2. Schizoaffective Disorder or Schizophrenia (if not properly managed) Why contraindicated: SSRIs may worsen psychosis in some cases by increasing serotonin and dopamine tone. Precaution: Use only under antipsychotic cover and clear depressive component. 3. Serotonin Syndrome Risk (esp. in Polypharmacy) Why contraindicated: SSRIs combined with other ...
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